This interface is ideal when using more than 16 channels from a console in MADI - 16 format. The MADI-16 is a package of one IEX16L-A with the RME ADI-648 MADI to ADAT interface. For more than 16 channels, simply add one more IEX16L-A per 16 channels for a maximum of 64 channels. MADI, ADAT and the myMix protocol are all 24-bit/48kHz signals so no audio signal quality is lost due to sample rate conversion.
As the myMix system generates its own clock, there is no need to feed any master clock: simply connect the MADI cable to the ADI-648 input and use TOSLINK cables to forward the signals to the IEX16L-A. If you use multiple IEX16L-A with the ADI-648 you might want to consolidate them with a switch to return a single CAT5(6) cable to the main switch. Ideal models are the Power8 and the Multi 8.